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    • Combining Macroscopic and Molecular Techniques: A Unified Strategy for Targeted Tumor Therapy  
      Alda L. Tam, M.D., M.B.A., of The University of Texas MD Anderson Cancer Center, was awarded a 2012 RSNA Research Seed Grant to develop her project, “Optimizing Techniques and Imaging Evaluation of Combination Locoregional Therapy in Rabbit VX2 Hepatic Tumors using Radiolabeled Nanoparticles.”

       

      This study is designed to investigate the tumoral uptake of hollow gold nanoparticles loaded with doxorubicin when combined with either irreversible electroporation (IRE) or radiofrequency ablation (RFA). “This RSNA Seed Grant has made it possible to study whether the unique properties of IRE and nanoparticle technology can be integrated to create a better treatment platform for liver tumors, providing the critical information needed to translate this research concept into human clinical trials.”