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    February 01, 2014

    Press releases were sent to the medical news media for the following articles appearing in recent issues of Radiology.

    MR images in 45-year-old woman with glioblastoma
    (Click to enlarge) MR images in 45-year-old woman with glioblastoma treated with surgery, chemotherapy and radiation therapy. Unenhanced T1-weighted image shows high-signal-intensity globus pallidus. Standard ROIs were placed around globus pallidus and thalamus.
    (Radiology 2014;271;InPress) ©RSNA, 2014. All rights reserved.Printed with permission. 

    High-signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-weighted MRI: Relationship with Increasing Cumulative Dose of a Gadolinium-based Contrast Material

    High-signal intensity in the dentate nucleus (DN) and globus pallidus (GP) on unenhanced T1-weighted images may be a consequence of the number of previous gadolinium-based contrast material administrations, according to new research.

    In the study, Tomonori Kanda, M.D., Ph.D., of the Hyogo Cancer Center, Akashi, Japan, and colleagues compared unenhanced T1-weighted MR images (T1WI) of 19 patients who had undergone six or more contrast-enhanced brain scans with 16 patients who had received six or fewer unenhanced scans. The hyperintensity of both the DN and the GP correlated with the number of gadolinium-based contrast material administrations.

    Results showed high-signal intensity of both the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images correlates with the number of previous gadolinium-based contrast medium administrations (dentate nucleus: P < .001, regression coefficient = 0.010, 95 percent confidence interval [CI]: 0.009, 0.011; globus pallidus: P < .001, regression coefficient = 0.004, 95 percent CI: 0.002, 0.006).

    “Gadolinium deposition, or high-signal intensity material deposition related to cumulative gadolinium load, occurs in the human brain independent of renal function,” the authors write.

    Axial T2-weighted (left) and sagittal T1-weighted (right) MR images
    (Click to enlarge) Axial T2-weighted (left) and sagittal T1-weighted (right) MR images show position and orientation of posterior white matter point-resolved spectroscopy voxel.
    (Radiology 2014;270;2:InPress) ©RSNA, 2014. All rights reserved. Printed with permission. 

    White Matter NAA/Cho and Cho/Cr Ratios at MR Spectroscopy Are Predictive of Motor Outcome in Preterm Infants

    The combination of choline/creatine (Cho/Cr) and N-acetylaspartate (NAA) ratios measured in the posterior periventricular white matter at term-equivalent age is predictive of motor outcome at 1 year in infants born at less than 32 weeks gestation, new research shows.

    Giles S. Kendall, M.R.C.P.H., Ph.D., of the University College London, and colleagues examined 43 infants (24 boys) born at less than 32 weeks gestation and admitted for neonatal intensive care. Researchers performed single-voxel point-resolved proton (hydrogen 1) MR spectroscopy from a 2-cm3 voxel centered in the posterior periventricular white matter.

    Abnormal motor outcome at 1 year can be predicted with a cerebral white matter N-acetylaspartate (NAA)–to-choline (Cho) ratio of less than 0.725 and a Cho-to-creatine (Cr) ratio of more than 2.425 at proton MR spectroscopy performed at term-corrected age, results showed. An increased Cho/Cr ratio and a decreased NAA/Cho ratio can predict impaired motor outcome at a corrected age of 1 year, with a sensitivity of 0.80 (95 percent confidence interval [CI]: 0.57, 0.94) and specificity of 0.80 (95 percent CI: 0.66, 0.88).

    “Cho/Cr and NAA/Cho ratios have the potential to be used as surrogate endpoints in neuroprotection trials in preterm babies; in addition, they may indicate at an early stage those babies who may benefit from ongoing intervention in infancy,” the authors concluded.

    Media Coverage of RSNA

    Radiology January 2014In November, 3,592 RSNA-related news stories were tracked in the media. These stories reached an estimated 1 billion people.

    Coverage included The Huffington Post, U.S. News & World Report – Online, The Wall Street Journal – Online, Chicago Tribune – Online, The Virginian-Pilot, Science, NBCNews.com, MSN Health, Reuters.com, ABCNews.com and Yahoo! Finance.

    Read coverage of RSNA in these media:

    RadiologyInfo.orgNew on RadiologyInfo.org

    Visit RadiologyInfo.org, the public information website produced by the RSNA and ACR, to read the recently posted content on anemia. For more information, go to: www.radiologyinfo.org/en/info.cfm?pg=anemia.

    Marcom AwardsRSNA Wins MarCom Awards

    RSNA received five 2013 MarCom Awards from the Association of Marketing & Communication Professionals, an international awards competition that recognizes outstanding creative achievement.

    Platinum Awards: 

    • RSNA 2012 Press Kit
    • A television segment about an RSNA 2012 study on the “chemo brain” phenomenon that appeared on the NBC Nightly News.

    Gold Awards: 

    • RSNA News — the July 2013 issue highlighting the role of radiology in aiding victims of the 2013 Boston bombing
    • RSNA Employee Intranet

    Honorable Mention: 

    For more information, go to www.marcomawards.com.

    February Public Information Outreach Activities Focus on Heart Health

    February is American Heart Month and the RSNA “60-Second Checkup” radio program, distributed to nearly 100 radio stations across the country, will focus on the use of coronary CTA to reveal similarities of heart disease in men and women.

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